Synthesis of Enaminones by a Palladium-Catalyzed Four-Component Carbonylative Addition Reaction
نویسندگان
چکیده
منابع مشابه
A convenient and general palladium-catalyzed carbonylative coupling for the synthesis of 2-arylbenzoxazinones.
Benzoxazinones represent a class of annulated nitrogen heterocycles that are of interest to organic synthesis owing to their various biological activities. Among the different methodologies developed for their preparation, cyclization of anthranilic acid, N-acylanthranilic acid, or isotonic anhydride are most accepted. Although alternative methodologies are known, the availability of substrates...
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An efficient procedure for 2-aroylbenzofuran preparation from 2-bromophenols, phenacyl bromides and paraformaldehyde is described. The cheap and stable paraformaldehyde served as the carbon source via an in situ formylation reaction.
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Palladium-catalyzed processes have proven to be a powerful and useful tool for the synthesis of heterocycles. Palladium has found such wide utility because it affects an extraordinary number of very different reactions, including many carbon-carbon bond-forming reactions, under relatively mild reaction conditions. Furthermore, palladium can usually be used in only catalytic amounts and tolerate...
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We developed a palladium-catalyzed carbonylative Sonogashira reaction with aryl triazenes and alkynes as substrates and methanesulfonic acid as the additive. A series of α,β-ynones were synthesized by this alternative procedure. Notably, bromides, iodides and hydroxyl groups could be well-tolerated under these reaction conditions.
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An efficient one-pot four-component protocol for the synthesis of pyrano[2,3-c]pyrazolederivatives has been demonstrated using Y(NO3)3.6H2O as catalyst under mild condition. This isa general synthetic protocol which could be applicable to a wide range of carbonyl compoundsincluding aromatic aldehydes, isatins and acenaphthenequinone. All The reactions proceededsmoothly, ...
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ژورنال
عنوان ژورنال: Synlett
سال: 2017
ISSN: 0936-5214,1437-2096
DOI: 10.1055/s-0036-1590976